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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ee423a79e38f35279fa52f0d872a18b49df04f244cd3a66e984566e031d7f45' 
  AND token = 'QO01KtV5lnmVdKLVnM1d+xI9z2dTWMIEgaIwDrji5ys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}