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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91f745592310a9b8f09022ce4913e06a197e2bf665019cf3ca7ac8deb2992a20' 
  AND token = 'RFGWWl0G7pQb7waMBJ4FS8IWfGbVIwnMSBrbjj+vhZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}