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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22d2d15b7c441212eaf010b3908f000df9bda3782089f9e9ff50408bf8b8fe4c' 
  AND token = 'i65bKEfStOmezVmfTfXGnAT7ZkKowFVLKB0aBJxGdII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}