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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9039e33a4a2edeba3820654dc747e1a52af429e2d4e0a096ac7a17e5b3725469' 
  AND token = '14SYDIaQ1+Vs5CMRICcTbfYM8+4hK4Wn9+16an8jRpE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}