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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3db43cb1ca72fa527379034ef36f4e99928fced51bf6c2b29c721ec32a14fae1' 
  AND token = 'ZK2N6OqGkLwbq4IC5RS8CC7xzd0YQbBpQsf4aHJor7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}