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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b227ccca39546650a94f45fb3ff8ea9b18b860ace63a26538309224d9cda872' 
  AND token = 'Eq9oipb+CMdvnil8khqnTA7SLtzyolcxIr87qLMdB2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}