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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a24470a6e5c52178e1269dc15273c5af162fb5e67d20406af1fa1a067cd9d7d5' 
  AND token = 'Nmm6y6F5uxkF2Qqt+4o0J6pFDscqcXLCDAFEVR48Th0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}