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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8043af8e16f5f61d8d72fa501c46601b64481b4adf68b83c8b3c0c4445f83803' 
  AND token = 'znLny0Ju5n3qrhKLwt+EdGUo0qF1EiOjIoHDO1hUYsI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}