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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af5822c85adcf549e00ff6fe6c751a815247e83840b2771eef0a1413ae84e188' 
  AND token = 'f+m7QjBctjYflIoan12GSHoQfeq2l91drcaFCupFyUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}