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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d0a08ad6916d46bff17d79e3ecb70f9bffc9b0d4cdefa736152da4cfc7f1231' 
  AND token = 'qW5rGmqRkrzElmEZZO4XSL/cxtu69ngiDR1/dQ/puAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}