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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7cadb805f2b1171e3f000df65a02add957706ebf21a8da50e12e8695507f8d50' 
  AND token = '29zEMxaWcCX+OMdwFXtPb/ZQtgduWK9QRu8G+Aa0gro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}