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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c59e04c3ac8ac442ab4cd568b64747b9eebef6d30c3c158c1765bec500cfc945' 
  AND token = 'EqDUL4MZX0o3TMcZeJjf570LbLHqo+uSTKuInnTQRpw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}