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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '470e73fffcab7d8c8c125ec08039ccb2df8670c4137772c2c77027bc5661d6f9' 
  AND token = 'czW5pUt4BHcj05EDjtZR1MwpUsN7fnx6+Gmk7XhDxjo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}