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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c22048d49dcab065edda730d1feb6c6cf2b5398811367bcc8bb26aca5eef2e4' 
  AND token = 'DKq1h03kLdj+na0JuaIvHIpGvts7zuUd4IqyAwU5a/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}