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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4342232d600adb2a3ede52d82b7c87805654af52357f1a4867572640b93726a7' 
  AND token = 'bgacLa/Y0NSyR7mC1NTfsrQG8uFYZajjAwpA3z6u1Is=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}