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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a0736d90a925eaf35c9df9c62b57b0a476d6b88b2c2f6197fe7f5ef3e74044a' 
  AND token = 'FQvOmADxi+6MMT4+6PixfB3cBQjN70qjbxL8VbkcUDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}