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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0eea0baa4b13377330f40503f308a7d2d464f3f4483b555f914c3d07519e2f37' 
  AND token = 'xIAaOYyPiCYbZigoZ7aI+JrcL790qnOJvdv2OoRmCaU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}