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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77e82a8349e0096778aa3e681b23e6ef074048f61c15ba019d0443529388d29c' 
  AND token = '7KjYNeZiiBMVmN6Tr1071vS9MraeDLm5SbAJ8XLw6lM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}