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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a52535e764bc7c35e12510b1ce8df131220aacae9f4af5569a13c3f86e00d10' 
  AND token = 'rMNlH9au/8lmxHzB7SY+/fGZ5LDe5v0J9aTc3a2hKOY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}