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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '545928d7312de7342c28a246d3008f90404f6a1af93dc9c40b69d109178df8b1' 
  AND token = 'NDz+vWKOHx4D2xNFXql/Qc+7e66QiLzZPAQiqk8Rac0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}