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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e34e22d950956a36408cefc3708dd8e2dc46a3838fd58f3a33c3b83fd4a0ac52' 
  AND token = '7LgCuWcD2QJDJtSvAb+bSb4qQ3wHdknbTt/eJALvPYQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}