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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d7d49192a3392838603f610fead6d1421363088b86333d43ce4b2a30508934d' 
  AND token = 'e/3vnmpDhMrNJKebMyFjCE8+hkscT2G6seqHBxRfjq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}