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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22e96398288c421fa8cd9c639853684c101d297e0fcc4a88dc427c7a6c8f0257' 
  AND token = 'e8prvfrL2qxUkvTyLV6jAcAhtmLPDtuJZZr5s6m3czE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}