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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d6904ec7b8c561f5c59ad9b14319596bc8787a01f4374bcc8ed8033ce4e8ca2' 
  AND token = 'ZvgI/4Z1rbXtW7762BfRIzLeGT0nVIr+vkdIkFIWGa0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}