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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '558e7d1facdc2b0e27588bd83334514da0518b6f1721acbdaaf180d358c7487c' 
  AND token = 'gn+tCN972RZpDCOwpFxKEe5yXBNa3Q5ZYewhKfCiyog=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}