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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e985136dd33b843df306d6cd3b5673a16ce65f0cd884fa07d65e65ee4ce0f1e7' 
  AND token = 'Y9Bo31qBtLFFfB3o4dT4Jgmk/G3qd72/vsPXNTihYHI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}