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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b39acfcf70f9bf1c1ef3cc8b80edd315f33e8452413163bd01f1d0d431b9d39d' 
  AND token = 'd3IresaOtu3pNAtBlPXqNhMq1LwFbFcBcZZciIT2LF0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}