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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cc94ed0bfb34f931ecbf3920e1a6c80558f3c743b6b683f565f0441a038e3ba' 
  AND token = '+MFGsyuf9br/w/TLay8uhodHOvHuw2Q6PMicES9M5mQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}