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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '295181e82bf4fe8e714a264f9b552ee71de9670a13e17c340eb976a3b4fd0497' 
  AND token = 'yIczedjbb0Wd6/rX/44zXlEQfYEIO2eE28u/A995Q8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}