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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c17f928f0ed7d312a5f4f31599fb65a2cd8e45b591b15a8944c9c3de29128c56' 
  AND token = 'qk+dTAfBi63nMp2pyOlXsqT7pBN0OD5dCQWYvlLOWWU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}