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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ebd49f7e43923c649d5f0ac2e573ba3da4e6bd83f3b97a9a043e49ad0eecae43' 
  AND token = 'tl9WvCvSh2XyKKk0l8jT59c83nGuhrRfwhRYvEk25jo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}