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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '269e6a3449cea4521e2fc44a8f870464b1fd905dfbb2668be2000bf3517e9cb2' 
  AND token = 'Ra3ur9HGSa/CibhQbc7DaHK43zZKdWzlevvplX1Hjko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}