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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77c9ae5a6cc2f979bec1b8cb844f72b9ba602a57a7fbc6e451d791238dc0533f' 
  AND token = 'D0+tMKSo0sdH13LmF/6Z3ogFjTa6wyLoKit6VTJbwK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}