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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25784ee8a799e7145a35acbf74ef2b1f0729d27057190d0e9c9e652d8a62ade4' 
  AND token = 'TNbpHl4f2Z0KIUKoizSmY8vsu9uLU2fD8AEGY9SshRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}