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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6770a6523a7496c5749c1bbb296692a4d71c99c95be41b3ae711466f6a1789c6' 
  AND token = 'Ni5xnDka61wWPLCZ4Elc7/KYHnBKDti60UQVcqFJ0XQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}