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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c12e4f9180e2861bfc9c223eb18b878b00d98be79d228640ea58703ffb9d6ac7' 
  AND token = 'i9kEjPBmeBJme7XAhtuXtQMULB6L+r0V3blHcMW0rD0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}