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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dea082d8923cbb6546654a2f8718c5f71e553158ae3bbf65162849d6845f46a0' 
  AND token = 'oYDNuPaGYbI9Vb/xkAQry2/bXX/QTirt23257nDa01w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}