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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '143f9a9c4fba91be7a44bc2e54f5a2b69024bf708cf6432779bf43d340ec6141' 
  AND token = 'r9QjOLWlrp9YIXETW5C8cW6G4mPEFyd+QYYRbWm3jTg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}