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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54fa7e1e6e33c3e75353c3a70f0f556ff0ce3d575323baa95d7def330ab40d4c' 
  AND token = 'gxqtVM1mF6OYpQG/gx0iGM44wk/5fNMvXBxusEEVB/g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}