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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecc0dfdce295cd62d2be460a48438a7dbc0e552f48cbb78b52772fd4cb27b267' 
  AND token = 'IuSqwPy5yZVn+qNJVGdnc1wKwyGwXEQbaAYMA8oH86M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}