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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5914f13d3a29ebffc1d8581ba8dd95c9d4d3a63987e700c13655bb0e32864473' 
  AND token = 'D8KUKAstP4XykTdyCTQMG9y5jRZWwMT8/nQsqaJ6P3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}