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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4995e01484f34a6aa9a8ed05e0455a0a534902e0e8d0d6346e865a619faee4bd' 
  AND token = 'sFYj86sd9NJIDzjmQps99Vlol5TyiAgZw5SdSb5aBaI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}