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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5eb62aca0812302ed30132bf8bae32c3277533dcca3d94c4385321b36206f0d2' 
  AND token = 'oNB3X74uXL4Io/YRRGVjCjkiiMyZk4mIU9W81NbvLVI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}