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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '541a5e458285dddbd715c277fceeebf349987483dbf964cba956a254925e63fa' 
  AND token = 'Zbb58fPw0TiN1sqkfEPnACcjm7Y2bp1dj8uFu1HDZX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}