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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c052de5d61ef9be57c0a174e382082ece4ad6da7cc51fca286e800b2188dd6f' 
  AND token = '74XheZkyjhJgC4iRr+kVEGBdSwvbfHK6ecjK7Pl1GEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}