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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9d93f87e05af9be4f839a87c00d78eafe5f12e2cd4d5bfc6c24c338194600e4' 
  AND token = 'vXI+zZvT9tf4VWzYbHn2dyANoX9kRdCysHqte3Ey83A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}