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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc4bc256e61dc9b981940b2e26ea7c037ed1ed34d7c78067ab27870aac0d8ec7' 
  AND token = 'PET4iFbkoDFFDviuGpbfaiIpfS9QlDUhrBZF+bS+lqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}