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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10541c81a049c30a5f9ed50640f7ea599c56f39fe3dcf201ef5afd8147494355' 
  AND token = 'D9Lfnx8jtc+6Lh25YYVGpJuc8lt3gvsDSNTCvEps84Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}