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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9cace6e0339dbd8474ead2a5cff0587654da5b5207fa71f46583325a5fd9b3e4' 
  AND token = 'pC7Cypdmkz86B29/OUJXrx4L/mzxSLXyTXTfD3/ezpc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}