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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60fc563f1da28bdbb671da8632400456b3bb1bc043bf0da45f71f3c48919c0e4' 
  AND token = '3Ns8tTGvjBEcC8RgKWp0F08KjLOm1hMBU46VwN7Uf5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}